021-51111890
购物车（0）
sales@molnova.cn
DAMGO (TFA)
CAS No. 950492-85-0
DAMGO (TFA) ( —— )
产品货号. M30306 CAS No. 950492-85-0
DAMGO is a selective peptide agonist of the μ-opioid receptor .
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥518 | 有现货 |
|
| 10MG | ￥936 | 有现货 |
|
| 25MG | ￥2009 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
生物学信息
-
产品名称DAMGO (TFA)
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述DAMGO is a selective peptide agonist of the μ-opioid receptor .
-
产品描述DAMGO is a selective peptide agonist of the μ-opioid receptor .
-
体外实验DAMGO (1-10 μM) TFA significantly reduces the activation of neuronal Akt and ERK1/2 by CXCL12 and inhibits CXCL12-promoted neuronal survival, but does not down-regulate CXCR4 protein expression.DAMGO (1 μM) TFA effectively inhibits the prostaglandin E 2 (PGE 2) induced increase in a tetrodotoxin-resistant voltage-gated Na+ current (TTX-R I Na), i.e. PGE 2 (1 μM) can increase the TTX-R I Na peak by 103 % compared to 24.9 % with the addition of DAMGO.
-
体内实验DAMGO (i.v., 0.5-2 mg/kg) TFA can produce significant anti-injury effects on injured paws of male Sprague-Dawley rats weighing 200-225 g in a dose-dependent manner, producing an effective and long-lasting analgesic effect.
-
同义词——
-
通路Endocrinology/Hormones
-
靶点Opioid Receptor
-
受体——
-
研究领域——
-
适应症——
化学信息
-
CAS Number950492-85-0
-
分子量627.61
-
分子式C28H36F3N5O8
-
纯度>98% (HPLC)
-
溶解度H2O : 125 mg/mL (199.17 mM; Need ultrasonic)
-
SMILES——
-
化学全称Sequence:Tyr-{d-Ala}-Gly-{Me-Phe}-Gly-ol
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
FEBS Lett. 1995 Jan 2;357(1):93-7. Onogi T, et al. DAMGO, a mu-opioid receptor selective agonist, distinguishes between mu- and delta-opioid receptors around their first extracellular loops.
产品手册
关联产品
-
DAA1106
DAA1106 是外周苯二氮卓受体 (PBR) 的有效选择性配体，可作为外周苯二氮卓受体的有效选择性激动剂。
-
[Arg14,Lys15]Nocicep...
Highly potent and selective NOP receptor agonist (EC50 = 1 nM). Displays > 875-fold selectivity over opioid receptors (IC50 values are 0.32, 280, > 10000 and 1500 for NOP, μ, δ and κ receptors respectively). Longer lasting and 30-fold more potent than nociceptin in vivo; pronociceptive and inhibits locomotor activity.
-
Naloxone hydrochlori...
盐酸纳洛酮是一种阿片类反激动剂化合物，用于对抗阿片类化合物过量的影响。
